Pakistan won the three-match series 2-1 after winning the first two ODIs in Chennai and Kolkata.
Misbah blamed the cold weather conditions for his team's 10-run loss to India in the Kotla match.
"I said at the toss that it's the weather that is really deceiving us. The pitch looked like it's a batting track but it was almost five or six degrees. We didn't expect this kind of moisture in the pitch," said Misbah.
The dejected skipper said that his side missed the golden chance of a whitewash.
"The way the Indian team fielded, bowled and exploited the conditions, they saved almost 30-35 runs," he said.